Pubblicazioni

Autori:

Maluta, Tommaso; Lavagnolo, Umberto; Segalla, Lydia; Elena, Nicholas; Bernardi, Paolo; Degl'Innocenti, Daniele; Sbarbati, Andrea; Magnan, Bruno

Titolo:

Evaluation of biocompatibility, osteointegration and biomechanical properties of the new Calcemex® cement: an in vivo study

Anno:

2022

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

Elettronico

Referee:

Sì

Nome rivista:

EUROPEAN JOURNAL OF HISTOCHEMISTRY

ISSN Rivista:

2038-8306

N° Volume:

66

Numero o Fascicolo:

3313

Intervallo pagine:

1-7

Parole chiave:

polymethylmetacrilate; calcium phosphate cement; osteointegration; osteoconduction; biocompatibility; compression; environmental scanning electron microscopy

Breve descrizione dei contenuti:

The mixture of polymethylmethacrylate (PMMA) and β-tricalciumphospate (β-TCP) is the most widely used bone graft. Common features of bone cement are the biocompatibility, bioactivity, mechanical stability and ability to fuse with the host's bone tissue. However, there are still few studies that have evaluated these characteristics in vivo. Our study aims to acquire these parameters, using an animal model with functional characteristics similar to those of humans. The analyzed cement is Calcemex®, evaluated both in compact and fluid formulation. The chosen animal models were 5 pigs, treated with femoral and tibial implants of Calcemex® samples. After one year, the pigs were sacrificed and the specimens explanted for morphological, histological, ultrastructural and mechanical evaluations. For both formulations, the investigation highlighted the absence of foreign body reactions in the host, the histological integration with the surrounding tissues and the preservation of mechanical compression resistance.

Pagina Web:

https://doi.org/10.4081/ejh.2022.3313

Id prodotto:

124694

Handle IRIS:

11562/1056897

ultima modifica:

15 novembre 2022

Citazione bibliografica:

Maluta, Tommaso; Lavagnolo, Umberto; Segalla, Lydia; Elena, Nicholas; Bernardi, Paolo; Degl'Innocenti, Daniele; Sbarbati, Andrea; Magnan, Bruno, Evaluation of biocompatibility, osteointegration and biomechanical properties of the new Calcemex® cement: an in vivo study «EUROPEAN JOURNAL OF HISTOCHEMISTRY» , vol. 66 , n. 3313 , 2022 , pp. 1-7

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