Pubblicazioni

Autori:

Torazzi, Alessandro; Tedesco, Erika; Ceccato, Sofia; Santin, Laura; Campagnari, Simone; Losso, Lorenzo; Toldo, Silvia; Casari, Rebecca; Arzenton, Elena; Marini, Paola; Chiamulera, Cristiano; Lugoboni, Fabio

Titolo:

Safety and efficacy of CyTisine for smoking cessation in a hOSPital context (CITOSP): study protocol for a prospective observational study

Anno:

2024

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

Elettronico

Referee:

No

Nome rivista:

FRONTIERS IN PUBLIC HEALTH

ISSN Rivista:

2296-2565

N° Volume:

12

Intervallo pagine:

1-8

Parole chiave:

cost-effective; cytisine; hospital setting; protocol; safety; smoking cessation; tobacco addiction

Breve descrizione dei contenuti:

: Tobacco addiction is the primary preventable factor contributing to global mortality, and nicotine is one of the substances with the greatest potential for addiction. With a strong affinity for the α4β2 subtype receptor, cytisine (CYT) functions as a partial agonist of the acetylcholine nicotinic cholinergic receptor. It counteracts the effects of nicotine without causing any withdrawal symptoms. These features, combined with its limited mild adverse effects and minimal drug-drug interactions, make cytisine a cost-effective treatment for smoking cessation. The current protocol describes a prospective observational study on the safety and efficacy of CYT administered to inpatient smokers of the Integrated University Hospital of Verona (IUHVR), Veneto (Italy). This is a monocentric, observational, and prospective study on both sex smokers over the age of 18 years admitted to the IUHVR who meet the criteria for recruitment and have given their consent. Eligible participants will be assigned to the CYT intervention based on the West dosing schedule and will be followed up for 12 months from treatment initiation. Evaluation of safety, efficacy, and compliance will be assessed at 7 and 25 days, with follow-up at 3, 6, and 12 months from the start of the treatment (quit day). During each visit, any adverse events or adverse reactions reported by patients following the intake of CYT will be evaluated. This study will contribute, for the first time, to the knowledge about the use of CYT for smoking cessation in a hospital setting.

Id prodotto:

141918

Handle IRIS:

11562/1143666

ultima modifica:

20 dicembre 2024

Citazione bibliografica:

Torazzi, Alessandro; Tedesco, Erika; Ceccato, Sofia; Santin, Laura; Campagnari, Simone; Losso, Lorenzo; Toldo, Silvia; Casari, Rebecca; Arzenton, Elena; Marini, Paola; Chiamulera, Cristiano; Lugoboni, Fabio, Safety and efficacy of CyTisine for smoking cessation in a hOSPital context (CITOSP): study protocol for a prospective observational study «FRONTIERS IN PUBLIC HEALTH» , vol. 12 , 2024 , pp. 1-8

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