Pubblicazioni

Autori:

Tadiotto, Elisa; Maines, Evelina; Degani, Daniela; Balter, Rita; Bordugo, Andrea; Cesaro, Simone

Titolo:

Bone marrow features in Pearson syndrome with neonatal onset: A case report and review of the literature

Anno:

2018

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Referee:

No

Nome rivista:

PEDIATRIC BLOOD & CANCER

ISSN Rivista:

1545-5009

N° Volume:

65

Numero o Fascicolo:

4

Intervallo pagine:

1-4

Parole chiave:

Pearson syndrome; bone marrow; hypocellularity; neonatal; ringed sideroblasts; vacuolization of hematopoietic precursors

Breve descrizione dei contenuti:

Pearson syndrome (PS) is a rare mitochondrial disorder that usually presents with transfusion-dependent macrocytic anemia, exocrine pancreatic dysfunction, and lactic acidosis. Typical bone marrow (BM) features are vacuolization in hematopoietic progenitors, hypocellularity, and ringed sideroblasts. At the neonatal age, PS may have a variable clinical onset. Moreover, there is little information about BM features at this age and the timing of their presentation. We report a neonatal case of PS that presented with refractory anemia and atypical BM features. We reviewed the BM findings in neonatal-onset PS cases to stress the importance and limitations of BM evaluation at this age.

Note:

The page range is based on PDF FILE available on the journal website

Id prodotto:

109276

Handle IRIS:

11562/997254

ultima modifica:

18 novembre 2022

Citazione bibliografica:

Tadiotto, Elisa; Maines, Evelina; Degani, Daniela; Balter, Rita; Bordugo, Andrea; Cesaro, Simone, Bone marrow features in Pearson syndrome with neonatal onset: A case report and review of the literature «PEDIATRIC BLOOD & CANCER» , vol. 65 , n. 4 , 2018 , pp. 1-4

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo