Pubblicazioni

Autori:

Pighi, Laura; Salvagno, Gian Luca; Bertoldi, Nicole; Henry, Brandon M; Lippi, Giuseppe

Titolo:

Clinical assessment of Ortho VITROS SARS-CoV-2 antigen chemiluminescence immunoassay

Anno:

2024

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

Elettronico

Referee:

Sì

Nome rivista:

DIAGNOSIS

ISSN Rivista:

2194-8011

N° Volume:

11

Numero o Fascicolo:

2

Intervallo pagine:

200-202

Parole chiave:

COVID-19, SARS-CoV-2, diagnosis, immunoassay, laboratory medicine

Breve descrizione dei contenuti:

Given the clear awareness that COVID-19 has not disappeared but is here to stay, fast, high-throughput and relatively low-cost diagnostic techniques are likely to drive the market in the foreseeable future. The results of our clinical evaluation of the Ortho VITROS SARS-CoV-2 antigen chemiluminescence immunoassay during the time of circulating highly mutated SARS-CoV-2 variants such as BA.2.86 and JN.1 confirms the good performance of this technique in the diagnosis of acute SARS-CoV-2 infection, with cumulative accuracy and diagnostic sensitivity at the manufacturer’s cut-off value being 77 % and 72 %, respectively, which is in line with values reported in a previous meta-analysis when earlier SARS-CoV-2 variants were actively circulating. The accuracy and sensitivity in samples from patients with high viral load, who are thought to be the main carriers of SARS-CoV-2 transmission, was even better, showing a near perfect agreement with the molecular biology reference technique and a sensitivity of 95.6 %, which would allow fast, efficient and relatively inexpensive identification of super-spreaders.

Pagina Web:

https://www.degruyter.com/document/doi/10.1515/dx-2023-0182/html

Id prodotto:

137266

Handle IRIS:

11562/1117507

ultima modifica:

10 maggio 2024

Citazione bibliografica:

Pighi, Laura; Salvagno, Gian Luca; Bertoldi, Nicole; Henry, Brandon M; Lippi, Giuseppe, Clinical assessment of Ortho VITROS SARS-CoV-2 antigen chemiluminescence immunoassay «DIAGNOSIS» , vol. 11 , n. 2 , 2024 , pp. 200-202

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