Pubblicazioni

Autori:

Guglielmi A; Ruzzenente A; Campagnaro T; Pachera S; Valdegamberi A; Capelli P; Pedica F; Nicoli P; Conci S; Iacono C.

Titolo:

Does intrahepatic cholangiocarcinoma have better prognosis compared to perhilar cholangiocarcinoma?

Anno:

2010

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Nazioni degli autori:

ITALIA

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

Journal of Surgical Oncology

ISSN Rivista:

0022-4790

N° Volume:

101

Numero o Fascicolo:

2

Intervallo pagine:

111-115

Codice PMID:

19953578

Parole chiave:

cholangiocarcinoma, liver, surgery

Breve descrizione dei contenuti:

BACKGROUND AND OBJECTIVES: Cholangiocarcinoma can be classified as intrahepatic (ICC) or perihilar (PCC). The objectives of this study is to evaluate the surgical outcomes of patients with PCC and ICC, identify the main prognostic factors related to survival and compare the outcome and the prognostic factors of PCC and ICC. METHODS: Ninety-five out of 152 patients observed between January 1990 and December 2007 at Surgical Division of University of Verona Medical School underwent the resection of ICC (33 patients) or PCC (62 patients). RESULTS: Overall median survival was 24 months with a 3- and 5-year survival rate of 45% and 23%, respectively. Prognostic factors for survival were macroscopic types of the tumor, the resection of extrahepatic bile duct, radical resection, lymph node metastases, and macro-vascular invasion. Survival was related with the macroscopic type of the tumors with a 5-year survival rate of 26% and 13% for ICC and PCC, respectively. Univariate analysis identified that negative clinico-pathological factors where significant more frequently found in PCC compared to ICC. CONCLUSION: We identified that ICC have longer survival rate compared to PCC. PCC showed a higher frequency of negative clinico-pathological factors such as non-radical (R+) resection, perineural infiltration and macro-vascular invasion.

Id prodotto:

64071

Handle IRIS:

11562/342729

depositato il:

3 febbraio 2012

ultima modifica:

2 novembre 2016

Citazione bibliografica:

Guglielmi A; Ruzzenente A; Campagnaro T; Pachera S; Valdegamberi A; Capelli P; Pedica F; Nicoli P; Conci S; Iacono C., Does intrahepatic cholangiocarcinoma have better prognosis compared to perhilar cholangiocarcinoma? «Journal of Surgical Oncology» , vol. 101 , n. 2 , 2010 , pp. 111-115

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