Multidisciplinary and multi-center study (7 hospitals involved) for the development of a specific questionnaire for the assessment of the quality of life of patients with ileal bladder and topical orthopedics (Ileal Orthotopic Neo-Bladder IOB). The work of the group, which will also involve centers in other European countries in the future, will be divided into the following phases: 1) creation and selection of items; 2) drawing of the QoL questionnaire; 3) international adaptation; 4) Survey to test the psychometric properties of the instrument; 5) dissemination and planning of further research initiatives. Scientific Directors: M. Niero, Department of TeSIS - Sociology Section, University of Verona; S. Siracusano, Faculty of Medicine, University of Trieste