Publications

Authors:

Pieropan, Sara; Antoniazzi, Franco; Tadiotto, Elisa; Caldonazzi, Federico; Maschio, Maddalena; Aiello, Giulia; Melotti, Giulia; Cavarzere, Paolo; Piacentini, Giorgio

Title:

Bone Marrow Foot Oedema in Adolescents: The Role of Vitamin D

Year:

2019

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

Journal Bone Metabolism

ISSN of journal:

2287-6375

N° Volume:

26

Number or Folder:

4

Page numbers:

241-246

Keyword:

Bone marrow oedema; Child; Magnetic resonance imaging; Vitamin D

Short description of contents:

BACKGROUND: Bone marrow oedema (BMO) in children/adolescents is a rare clinical condition without an etiologic cause. It is associated with typical increased signal intensity on T2-weighted magnetic resonance images (MRI) and an increase in bone turnover in which vitamin D plays a pivotal role. No treatment guidelines for these young patients are to date available. METHODS: We performed a retrospective study in a pediatric setting of 13 patients with diagnosis of primary BMO of the foot on the basis of clinical and radiological findings. Data collection included sex, age, patient history, symptoms at presentation, clinical examination, laboratory bone turnover markers, vitamin D levels, MRI, treatment, and outcome. RESULTS: Vitamin D deficiency or insufficiency was found in 76.9% of cases. All patients were treated with adequate vitamin D daily intake, a short course of analgesic therapy, physical therapy, avoiding detrimental feet and ankle immobilization. All fully recovered in 3-month lag period. CONCLUSIONS: Our data highlight that environmental factors, such as underestimated articular or bone microtraumatisms, as well as joint hyper mobility, in a bone turnover milieu of vitamin D deficiency could be the cause of this clinical conditions. Adequate vitamin D supplementation, associated with physical and analgesic therapy, is crucial in the management of BMO.

Web page:

http://dx.doi.org/10.11005/jbm.2019.26.4.241

Product ID:

115054

Handle IRIS:

11562/1019994

Last Modified:

November 15, 2022

Bibliographic citation:

Pieropan, Sara; Antoniazzi, Franco; Tadiotto, Elisa; Caldonazzi, Federico; Maschio, Maddalena; Aiello, Giulia; Melotti, Giulia; Cavarzere, Paolo; Piacentini, Giorgio, Bone Marrow Foot Oedema in Adolescents: The Role of Vitamin D «Journal Bone Metabolism» , vol. 26 , n. 4 , 2019 , pp. 241-246

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