Publications

Authors:

Venturi, Gabriele; Pighi, Michele; Lunardi, Mattia; Mainardi, Andrea; DEL SOLE, PAOLO ALBERTO; Tavella, Domenico; Setti, Martina; Pesarini, Gabriele; Benini, Annachiara; Ferrero, Valeria; Scarsini, Roberto; Ribichini, Flavio Luciano

Title:

Contrast-Induced Nephropathy in Patients Undergoing Staged Versus Concomitant Transcatheter Aortic Valve Implantation and Coronary Procedures

Year:

2021

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE

ISSN of journal:

2047-9980

N° Volume:

10

Number or Folder:

15

Page numbers:

1-10

Keyword:

"cardiology"; "interventional cardiology"; "TAVI"; "structural valve interventions"; "acute kindey injury"

Short description of contents:

BACKGROUND: The impact of staged versus concomitant coronary procedures on renal function in patients with aortic stenosis undergoing transcatheter aortic valve implantation (TAVI) remains unclear. METHODS AND RESULTS: Three-hundred thirty-nine patients undergoing coronary procedures and TAVI as a staged strategy (160, 47.2%) or concomitant strategy (179, 52.8%) were retrospectively analyzed. Contrast-induced acute kidney injury (CI- AKI) occurred in 49 patients in the staged strategy group (30.6%) and in 18 patients (10.1%) in the concomitant strategy group (P<0.001). Among the staged strategy group, 25 (15.6%) patients developed CI-AKI after coronary angiography or percutaneous coronary intervention, 17 (10.6%) after TAVI, and 7 (4.3%) after both the procedures. Staged strategy was associated with a higher risk of CI-AKI (odds ratio, 3.948; P<0.001) after adjustment for multiple confounders and regardless of the baseline renal function (P for interaction=0.4) when compared with the concomitant strategy. At a median follow-up of 24.0 months (3.0–35.3), CI-AKI was not associated with sustained renal injury (P=0.794), irrespective of the adopted strategy. The concomitant strategy did not impact the overall early safety at 30 days follow-up after TAVI compared to the staged strategy (P=0.609). CONCLUSIONS: Performing coronary procedures with a staged strategy before TAVI was associated with a higher risk of CI-AKI compared with a concomitant strategy. Moreover, a concomitant strategy did not increase the risk of procedure-related complications.

Product ID:

128090

Handle IRIS:

11562/1072288

Last Modified:

February 23, 2023

Bibliographic citation:

Venturi, Gabriele; Pighi, Michele; Lunardi, Mattia; Mainardi, Andrea; DEL SOLE, PAOLO ALBERTO; Tavella, Domenico; Setti, Martina; Pesarini, Gabriele; Benini, Annachiara; Ferrero, Valeria; Scarsini, Roberto; Ribichini, Flavio Luciano, Contrast-Induced Nephropathy in Patients Undergoing Staged Versus Concomitant Transcatheter Aortic Valve Implantation and Coronary Procedures «JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE» , vol. 10 , n. 15 , 2021 , pp. 1-10

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo