- Autori:
-
Castriota, F.; Tomai, F.; Gabrio Secco, G.; Reimers, B.; Piccoli, A.; De Persio, G.; Pesarini, G.; Schiavina, G.; Borioni, R.; Pacchioni, A.; Cremonesi, A.; Vassanelli, C.; Ribichini, F.
- Titolo:
-
Early and late clinical outcomes of endovascular, surgical, and hybrid revascularization strategies of combined carotid and coronary artery diseases: the FRIENDS study group (Finalized Research In ENDovascular Strategies)
- Anno:
-
2015
- Tipologia prodotto:
-
Articolo in Rivista
- Tipologia ANVUR:
- Articolo su rivista
- Lingua:
-
Inglese
- Referee:
-
No
- Nome rivista:
- EUROPEAN HEART JOURNAL SUPPLEMENTS
- ISSN Rivista:
- 1520-765X
- N° Volume:
-
17
- Numero o Fascicolo:
-
suppl A
- Intervallo pagine:
-
23-28
- Parole chiave:
-
endovascular, FRIENDS, combined carotid
- Breve descrizione dei contenuti:
- The best therapeutic strategy for patients with concomitant carotid obstructive disease (COD) and coronary artery disease (CAD) remains controversial. The aim of the study is to observe post-procedural and 1-year clinical outcomes of patients with COD and CAD after an endovascular, surgical, or a combined (hybrid) revascularization approach, selected by consensus of a multidisciplinary team. Between January 2006 and December 2012, 1043 consecutive patients with COD and concomitant CAD were treated. According to treatment strategies, patients were divided into three groups: surgical: 391 patients (37.1%), endovascular: 502 (48.1%), and hybrid (combined surgical and percutaneous revascularization): 129 (12.4%). The remaining 21 patients were managed medically only and not analysed. The primary end point of the study was a composite of death, myocardial infarction (MI), and stroke at 1-year follow-up; secondary end points included a composite of death, MI, and stroke in-hospital, and major bleeding complications. In hospital, mortality was higher in the surgical group (2.3 vs. 0.2 and 0%, P < 0.001), more strokes occurred in the endovascular group (2.0 vs. 0.5 and 0.8%, P = 0.03), and major bleedings were more frequent among hybrid patients (13.9 vs. 3.8 and 5.5%, P = 0.001). The incidence rate of the primary end point (hierarchical at 1 year) occurred in 6.0% of the study population (5.8, 6.5, and 4.6%, respectively; P = ns for all groups). Surgical and endovascular treatments yield remarkable clinical results both at acute and 1-year follow-up. The best-suited revascularization strategy should be discussed in a multidisciplinary context, and chosen according to the clinical characteristics of each single case and local expertise.
- Id prodotto:
-
132124
- Handle IRIS:
-
11562/1084246
- ultima modifica:
-
23 febbraio 2023
- Citazione bibliografica:
-
Castriota, F.; Tomai, F.; Gabrio Secco, G.; Reimers, B.; Piccoli, A.; De Persio, G.; Pesarini, G.; Schiavina, G.; Borioni, R.; Pacchioni, A.; Cremonesi, A.; Vassanelli, C.; Ribichini, F.,
Early and late clinical outcomes of endovascular, surgical, and hybrid revascularization strategies of combined carotid and coronary artery diseases: the FRIENDS study group (Finalized Research In ENDovascular Strategies)
«EUROPEAN HEART JOURNAL SUPPLEMENTS»
, vol.
17
, n.
suppl A
,
2015
,
pp. 23-28
Consulta la scheda completa presente nel
repository istituzionale della Ricerca di Ateneo