Publications

Authors:

Castriota, F.; Tomai, F.; Gabrio Secco, G.; Reimers, B.; Piccoli, A.; De Persio, G.; Pesarini, G.; Schiavina, G.; Borioni, R.; Pacchioni, A.; Cremonesi, A.; Vassanelli, C.; Ribichini, F.

Title:

Early and late clinical outcomes of endovascular, surgical, and hybrid revascularization strategies of combined carotid and coronary artery diseases: the FRIENDS study group (Finalized Research In ENDovascular Strategies)

Year:

2015

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

EUROPEAN HEART JOURNAL SUPPLEMENTS

ISSN of journal:

1520-765X

N° Volume:

17

Number or Folder:

suppl A

Page numbers:

23-28

Keyword:

endovascular, FRIENDS, combined carotid

Short description of contents:

The best therapeutic strategy for patients with concomitant carotid obstructive disease (COD) and coronary artery disease (CAD) remains controversial. The aim of the study is to observe post-procedural and 1-year clinical outcomes of patients with COD and CAD after an endovascular, surgical, or a combined (hybrid) revascularization approach, selected by consensus of a multidisciplinary team. Between January 2006 and December 2012, 1043 consecutive patients with COD and concomitant CAD were treated. According to treatment strategies, patients were divided into three groups: surgical: 391 patients (37.1%), endovascular: 502 (48.1%), and hybrid (combined surgical and percutaneous revascularization): 129 (12.4%). The remaining 21 patients were managed medically only and not analysed. The primary end point of the study was a composite of death, myocardial infarction (MI), and stroke at 1-year follow-up; secondary end points included a composite of death, MI, and stroke in-hospital, and major bleeding complications. In hospital, mortality was higher in the surgical group (2.3 vs. 0.2 and 0%, P < 0.001), more strokes occurred in the endovascular group (2.0 vs. 0.5 and 0.8%, P = 0.03), and major bleedings were more frequent among hybrid patients (13.9 vs. 3.8 and 5.5%, P = 0.001). The incidence rate of the primary end point (hierarchical at 1 year) occurred in 6.0% of the study population (5.8, 6.5, and 4.6%, respectively; P = ns for all groups). Surgical and endovascular treatments yield remarkable clinical results both at acute and 1-year follow-up. The best-suited revascularization strategy should be discussed in a multidisciplinary context, and chosen according to the clinical characteristics of each single case and local expertise.

Product ID:

132124

Handle IRIS:

11562/1084246

Last Modified:

February 23, 2023

Bibliographic citation:

Castriota, F.; Tomai, F.; Gabrio Secco, G.; Reimers, B.; Piccoli, A.; De Persio, G.; Pesarini, G.; Schiavina, G.; Borioni, R.; Pacchioni, A.; Cremonesi, A.; Vassanelli, C.; Ribichini, F., Early and late clinical outcomes of endovascular, surgical, and hybrid revascularization strategies of combined carotid and coronary artery diseases: the FRIENDS study group (Finalized Research In ENDovascular Strategies) «EUROPEAN HEART JOURNAL SUPPLEMENTS» , vol. 17 , n. suppl A , 2015 , pp. 23-28

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo