Publications

Authors:

De Rosa, Silvia; Sella, Nicolò; Rezoagli, Emanuele; Lorenzoni, Giulia; Gregori, Dario; Bellani, Giacomo; Foti, Giuseppe; Pettenuzzo, Tommaso; Baratto, Fabio; Fullin, Giorgio; Papaccio, Francesco; Peta, Mario; Poole, Daniele; Toffoletto, Fabio; Maggiore, Salvatore Maurizio; Navalesi, Paolo; Tiberio, Ivo; Pasin, Laura; Godi, Ilariak; Serra, Eugenio; Zarantonello, Francesco; Andreatta, Giulio; Boscolo, Annalisa; Persona, Paolo; Cattin, Lucia; Forin, Edoardo; Boni, Elisa; Golino, Gianlorenzo; Danzi, Vinicio; Vetrugno, Luigi; Cornacchia, Nicola; Donadello, Katia; Gottin, Leonardo; Polati, Enrico; Campagnolo, Matteo; Linassi, Federico; Panciera, Giulio; Garofalo, Eugenio; Bruni, Andrea; Carlon, Riccardo; Pipitone, Marilena; Serra, Elisabetta; Candosin, Antonio; Badii, Flavio; Role, Sandro Della; Girardis, Massimo; Busani, Stefano; Gamberini, Elisa; Tartivita, Chiara Natalia; Gamberini, Lorenzo; Cortegiani, Andrea; Frisella, Sara; Ippolito, Mariachiara; Salvo, Francesco; Greco, Massimiliano; Cecconi, Maurizio; Aceto, Romina; Langer, Thomas; Repishti, Marta

Title:

The PROVENT-C19 registry: A study protocol for international multicenter SIAARTI registry on the use of prone positioning in mechanically ventilated patients with COVID-19 ARDS

Year:

2022

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

PLoS ONE

ISSN of journal:

1932-6203

N° Volume:

17

Number or Folder:

12

Page numbers:

1-13

Keyword:

COVID-19; respiratory failure; prone position

Short description of contents:

Background: The worldwide use of prone position (PP) for invasively ventilated patients with COVID-19 is progressively increasing from the first pandemic wave in everyday clinical practice. Among the suggested treatments for the management of ARDS patients, PP was recommended in the Surviving Sepsis Campaign COVID-19 guidelines as an adjuvant therapy for improving ventilation. In patients with severe classical ARDS, some authors reported that early application of prolonged PP sessions significantly decreases 28-day and 90-day mortality. Methods and analysis: Since January 2021, the COVID19 Veneto ICU Network research group has developed and implemented nationally and internationally the "PROVENT-C19 Registry", endorsed by the Italian Society of Anesthesia Analgesia Resuscitation and Intensive Care…'(SIAARTI). The PROVENT-C19 Registry wishes to describe 1. The real clinical practice on the use of PP in COVID-19 patients during the pandemic at a National and International level; and 2. Potential baseline and clinical characteristics that identify subpopulations of invasively ventilated patients with COVID-19 that may improve daily from PP therapy. This web-based registry will provide relevant information on how the database research tools may improve our daily clinical practice. Conclusions: This multicenter, prospective registry is the first to identify and characterize the role of PP on clinical outcome in COVID-19 patients. In recent years, data emerging from large registries have been increasingly used to provide real-world evidence on the effectiveness, quality, and safety of a clinical intervention. Indeed observation-based registries could be effective tools aimed at identifying specific clusters of patients within a large study population with widely heterogeneous clinical characteristics. Trial registration: The registry was registered (ClinicalTrial.Gov Trials Register NCT04905875) on May 28,2021.

Note:

The page range is based on the pdf file available in the journal website.

Product ID:

132067

Handle IRIS:

11562/1085595

Last Modified:

October 31, 2024

Bibliographic citation:

De Rosa, Silvia; Sella, Nicolò; Rezoagli, Emanuele; Lorenzoni, Giulia; Gregori, Dario; Bellani, Giacomo; Foti, Giuseppe; Pettenuzzo, Tommaso; Baratto, Fabio; Fullin, Giorgio; Papaccio, Francesco; Peta, Mario; Poole, Daniele; Toffoletto, Fabio; Maggiore, Salvatore Maurizio; Navalesi, Paolo; Tiberio, Ivo; Pasin, Laura; Godi, Ilariak; Serra, Eugenio; Zarantonello, Francesco; Andreatta, Giulio; Boscolo, Annalisa; Persona, Paolo; Cattin, Lucia; Forin, Edoardo; Boni, Elisa; Golino, Gianlorenzo; Danzi, Vinicio; Vetrugno, Luigi; Cornacchia, Nicola; Donadello, Katia; Gottin, Leonardo; Polati, Enrico; Campagnolo, Matteo; Linassi, Federico; Panciera, Giulio; Garofalo, Eugenio; Bruni, Andrea; Carlon, Riccardo; Pipitone, Marilena; Serra, Elisabetta; Candosin, Antonio; Badii, Flavio; Role, Sandro Della; Girardis, Massimo; Busani, Stefano; Gamberini, Elisa; Tartivita, Chiara Natalia; Gamberini, Lorenzo; Cortegiani, Andrea; Frisella, Sara; Ippolito, Mariachiara; Salvo, Francesco; Greco, Massimiliano; Cecconi, Maurizio; Aceto, Romina; Langer, Thomas; Repishti, Marta, The PROVENT-C19 registry: A study protocol for international multicenter SIAARTI registry on the use of prone positioning in mechanically ventilated patients with COVID-19 ARDS «PLoS ONE» , vol. 17 , n. 12 , 2022 , pp. 1-13

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