Publications

Authors:

Mozzillo, Enza; Marigliano, Marco; Cuccurullo, Irene; Berchielli, Federica; Auricchio, Renata; Maffeis, Claudio; Maria Rosanio, Francesco; Iafusco, Dario; Pedrolli, Carlo; Pertile, Riccardo; Delvecchio, Maurizio; Passanisi, Stefano; Salzano, Giuseppina; Di Candia, Francesca; Franceschi, Roberto

Title:

Maintaining the gluten-free diet: The key to improve glycemic metrics in youths with type 1 diabetes and celiac disease

Year:

2023

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

Diabetes Research and Clinical Practice

ISSN of journal:

0168-8227

N° Volume:

207

Number or Folder:

111074

Page numbers:

1-7

Keyword:

Celiac disease; Glucose control; Maintaining GFD; Type1 diabetes mellitus

Short description of contents:

Aims: Gluten-free diets (GFD) were considered as high glycemic index and/or high content of saturated fats; this could affect keeping good metabolic control in individuals with both type 1 diabetes (T1D) and celiac disease (CD). Our objective was to analyze time in range and other continuous glucose monitoring (CGM) metrics with real-time CGM systems, in youths with T1D and CD, compared to those with T1D only. Methods: An observational case-control study, comparing youths aged 8-18 years with T1D and CD, with people with T1D only was performed. The degree of maintaining GFD was assessed through anti-tissue transglutaminase antibodies and dietary interview, and maintaining Mediterranean diet through the KIDMED questionnaire. Results: 86 youths with T1D and CD, 167 controls with T1D only, were included in the study and the two groups reported similar real-time CGM metrics. Among the first group, 29 % were not completely maintaining GFD and compared to people with T1D only they showed higher hyperglycemia rates (% time above range: 38.72 ± 20.94 vs 34.34 ± 20.94; P = 0.039). Conclusions: Individuals with T1D and CD who maintain GFD presented similar glucose metrics compared to youths with T1D only. Individuals not strictly maintaining GFD presented higher hyperglycemia rates.

Product ID:

137119

Handle IRIS:

11562/1116910

Last Modified:

February 20, 2024

Bibliographic citation:

Mozzillo, Enza; Marigliano, Marco; Cuccurullo, Irene; Berchielli, Federica; Auricchio, Renata; Maffeis, Claudio; Maria Rosanio, Francesco; Iafusco, Dario; Pedrolli, Carlo; Pertile, Riccardo; Delvecchio, Maurizio; Passanisi, Stefano; Salzano, Giuseppina; Di Candia, Francesca; Franceschi, Roberto, Maintaining the gluten-free diet: The key to improve glycemic metrics in youths with type 1 diabetes and celiac disease «Diabetes Research and Clinical Practice» , vol. 207 , n. 111074 , 2023 , pp. 1-7

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