Publications

Authors:

Pardo, A.; Vanti, V.; Lonardi, F.; Signoriello, A.; Lobbia, G.; Lombardo, G.; Trevisiol, L.; D'Agostino, A.

Title:

Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and oral microbiota (part 1)

Year:

2025

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

BMC ORAL HEALTH

ISSN of journal:

1472-6831

N° Volume:

25

Number or Folder:

1

Page numbers:

1-14

Keyword:

Cleft lip and/or palate; Oral microbiota; Periodontal parameters

Short description of contents:

Introduction Orofacial cleft impacts jawbone and dental development and function, often with consequences for oral health. The first in this two-part systematic review of the literature on oral health in persons with cleft lip and/or palate focuses on periodontal parameters and composition of oral bacterial flora, while the second analyzes data on dental caries.Materials and MethodsFour databases (PubMed, Cochrane, Scopus, Web of Science) were searched for studies that compared periodontal parameters, caries index, and microbiota composition between persons with cleft lip and/or palate and healthy controls. The Newcastle-Ottawa scale and the Joanna Briggs Institute checklist were applied to evaluate study quality.ResultsA total of 24 studies underwent systematic review, 18 of which entered meta-analysis. Twenty studies included a control group, while four included only persons with orofacial cleft. The first part (18 studies) compared periodontal parameters and oral microbiota.ConclusionsMeta-analysis of periodontal parameters (plaque index, gingival index, bleeding index, probing pocket depth, clinical attachment level) revealed an association between orofacial cleft and greater risk for poor oral health and periodontal disease. Good oral health relies on correct home oral hygiene and regular visits to the dentist starting at an early age.

Product ID:

144867

Handle IRIS:

11562/1158508

Last Modified:

March 27, 2025

Bibliographic citation:

Pardo, A.; Vanti, V.; Lonardi, F.; Signoriello, A.; Lobbia, G.; Lombardo, G.; Trevisiol, L.; D'Agostino, A., Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and oral microbiota (part 1) «BMC ORAL HEALTH» , vol. 25 , n. 1 , 2025 , pp. 1-14

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