Publications

Authors:

Fedele, Luigi; S., Bianchi; Raffaelli, Ricciarda; A., Portuese; M., Dorta

Title:

Treatment of adenomyosis-associated menorrhagia with a levonorgestrel-releasing intrauterine device

Year:

1997

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

Fertility and Sterility

ISSN of journal:

0015-0282

N° Volume:

68

Number or Folder:

3

Page numbers:

426-429

Keyword:

intrauterine; device; Progesterone; treatment; Adenomyosis

Short description of contents:

Objective: To evaluate the efficacy and tolerability of treatment with a levonorgestrel-releasing intrauterine device (IUD) in women affected by adenomyosis-associated menorrhagia. Setting: Tertiary care center. Design: Prospective, open, noncomparative study. Patient(s): Twenty-five women aged 38 to 45 years with recurrent menorrhagia associated with adenomyosis diagnosed at transvaginal ultrasonography participated in this study. Intervention(s): An IUD releasing levonorgestrel 20 mcg/day was inserted in each patient within 7 days of the start of menstrual flow. All of the patients were requested to compile a pictorial blood loss assessment chart each month. They underwent clinical and transvaginal ultrasound examinations 3, 6, and 12 months after IUD insertion. Main Outcome Measure(s): Menstrual pattern; serum hemoglobin, ferritin, and iron level changes. Result(s): One patient experienced IUD expulsion 2 months after device insertion and another requested removal of the IUD 4 months after insertion because of persistent irregular blood loss. Six months after IUD insertion, amenorrhea was observed in 2 patients and oligomenorrhea in another, spotting occurred occasionally in 7, and 13 had scanty but regular flow. One year of follow-up has been completed by the remaining 23 women: 2 with amenorrhea, 3 with oligomenorrhea, 2 with spotting, and 16 with regular flows. Significant increases in hemoglobin, hematocrit, and serum ferritin have been observed, but the lipid metabolism and clotting variables have remained unchanged. Conclusion(s): Our findings indicate that marked and safe relief from adenomyosis-associated menorrhagia can be obtained with the use of a levonorgestrel-releasing IUD.

Product ID:

2730

Handle IRIS:

11562/2730

Deposited On:

November 11, 2012

Last Modified:

November 30, 2022

Bibliographic citation:

Fedele, Luigi; S., Bianchi; Raffaelli, Ricciarda; A., Portuese; M., Dorta, Treatment of adenomyosis-associated menorrhagia with a levonorgestrel-releasing intrauterine device «Fertility and Sterility» , vol. 68 , n. 3 , 1997 , pp. 426-429

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo