Publications

Oral bisphosphonate-associated osteonecrosis of the jaw following implant surgery: a case report and literature review.  (2010)

Authors:
Bedogni, Alberto; Bettini, Giordana; Totola, Andrea; Saia, G.; Nocini, Pier Francesco
Title:
Oral bisphosphonate-associated osteonecrosis of the jaw following implant surgery: a case report and literature review.
Year:
2010
Type of item:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Language:
Inglese
Referee:
Name of journal:
Journal of Oral and Maxillofacial Surgery
ISSN of journal:
0278-2391
N° Volume:
68
Number or Folder:
7
Page numbers:
1662-1666
Keyword:
Oral bisphosphonate; osteonecrosis; implant surgery.
Short description of contents:
This report documents a case of bisphosphonate-related osteonecrosis of the jaw (BRONJ) after dental implant placement in an osteoporotic patient treated with alendronate for 6 years. A 63-year-old patient underwent rehabilitation of the posterior mandible with 2 dental implants in 2006 while taking alendronate to treat osteoporosis. The surgical procedure was uneventful. Both implants integrated well, and in November 2006 the patient wore a fixed partial prosthesis. Alendronate was never discontinued. In June 2008 a painful cheek swelling of the left mandible developed, associated with gingival bleeding. Since then, the patient underwent several courses of antibiotics, without relief of symptoms. In June 2009 the patient was referred to our department. An area of infected and exposed necrotic bone in the left mandible enclosed 1 dental implant. A panoramic radiograph and computed tomography scan showed an increased bone marrow density with peri-implant bone sequestration. The technetium Tc 99m scintigraphy–labeled granulocytes were positive for active bone infection. Bone exposure persisted for 8 weeks, and diagnosis of oral nitrogen-containing bisphosphonate (N-BP)–related osteonecrosis was made. On the basis of a review of the literature, this is the 10th case of BRONJ after implant placement in patients taking oral N-BPs. Despite the low risk of BRONJ occurrence after implant surgery in oral N-BP users, the fate of dental implants in these patients remains uncertain. Therefore patients at risk must be given a full explanation of the potential risks of implant failure and BRONJ development. Because the potential role of infection is still debated, great attention should be paid to the long-term oral hygiene of implant-prosthetic restorations
Product ID:
62262
Handle IRIS:
11562/363466
Deposited On:
March 29, 2012
Last Modified:
November 15, 2022
Bibliographic citation:
Bedogni, Alberto; Bettini, Giordana; Totola, Andrea; Saia, G.; Nocini, Pier Francesco, Oral bisphosphonate-associated osteonecrosis of the jaw following implant surgery: a case report and literature review. «Journal of Oral and Maxillofacial Surgery» , vol. 68 , n. 72010pp. 1662-1666

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo IRIS

Related projects
Title Department Managers
Allestimento di un modello osseo sperimentale in vitro per lo studio e la diagnosi della osteomielite dei mascelalri associata all'uso di aminobisfosfonati Department Ingegneria per la medicina di innovazione Pier Francesco Nocini, Alberto Bedogni
Studio quali/ quantitativo della composizione ossea dei mascellari di pazienti in trattamento cronico con aminobisfosfonati mediante valutazione istologica e istomorfometrica di campioni ossei prelevati in corso di estrazione di elementi dentali Department Ingegneria per la medicina di innovazione Alberto Bedogni
Valutazione dell'efficacia a distanza di un protocollo chirurgico demolitivo nel trattamento dell'osteonecrosi da bisfosfonati (2007) Department Scienze Chirurgiche Odontostomatologiche e Materno-Infantili Alberto Bedogni
<<back

Activities

Research facilities

Share