Publications

Authors:

Kinnunen, Eeva maija; Mosorin, Matti aleksi; Perrotti, Andrea; Ruggieri, Vito G; Svenarud, Peter; Dalén, Magnus; Onorati, Francesco; Faggian, Giuseppe; Santarpino, Giuseppe; Maselli, Daniele; Dominici, Carmelo; Nardella, Saverio; Musumeci, Francesco; Gherli, Riccardo; Mariscalco, Giovanni; Masala, Nicola; Rubino, Antonino S; Mignosa, Carmelo; De Feo, Marisa; Della Corte, Alessandro; Bancone, Ciro; Chocron, Sidney; Gatti, Giuseppe; Juvonen, Tatu; Biancari, Fausto

Title:

Validation of a New Classification Method of Postoperative Complications in Patients Undergoing Coronary Artery Surgery

Year:

2016

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

Sì

Name of journal:

Journal of Cardiothoracic and Vascular Anesthesia

ISSN of journal:

1053-0770

N° Volume:

30

Number or Folder:

2

Page numbers:

330-337

Keyword:

cardiac surgery, classification, complication, coronary artery bypass grafting, Aged, Aged 80 and over, Cardiac Surgical Procedures, Coronary Artery Bypass, Coronary Vessels, Endpoint Determination, Female, Humans, Male, Middle Aged, Postoperative Complications, Predictive Value of Tests, Prognosis, Retrospective Studies, Algorithms

Short description of contents:

Objective: The authors aimed to validate the European Multicenter Study on Coronary Artery Bypass Grafting (E-CABG) classification of postoperative Complications in patients undergoing coronary artery bypass grafting (CABG). Design: Retrospective, observational study. Setting: University hospital. Participants: A total of 2,764 patients with severe coronary artery disease. Complete baseline, operative, and postoperative data were available for patients who underwent isolated CABG. Interventions: Isolated CABG. Measurements and Main Results: The E-CABG complication classification was used to stratify the severity and prognostic impact of adverse postoperative events. Primary outcome endpoints were 30-day, 90-day, and long-term all cause mortality. The secondary outcome endpoints was the length of intensive care unit stay. Both the E-CABG complication grades and additive score were predictive of 30-day (area under the receiver operating characteristics curve 0.866, 95% confidence interval [CI] 0.829-0.903; and 0.876; 95% CI 0.844-0.908, respectively) and 90-day (area under the receiver operating characteristics curve 0.850, 95% CI 0.812-0.887; and 0.863, 95% CI 0.829-0.897, respectively) all-cause mortality. The complication grades were independent predictors of increased mortality at actuarial (log-rank: p < 0.0001) and adjusted analysis (p < 0.0001; grade 1: hazard ratio [HR] 1.757, 95% CI 1.111-2.778; grade 2: HR 2.704, 95% CI 1.664-4.394; grade 3: HR 5.081, 95% CI 3.148-8.201). When patients who died within 30 days were excluded from the analysis, this grading method still was associated with late mortality (p < 0.0001). The grading method (p < 0.0001) and the additive score (rho, 0.514; p < 0.0001) were predictive of the length of intensive care unit stay. Conclusions: The E-CABG postoperative complication classification seems to be a promising tool for stratifying the severity and prognostic impact of postoperative complications in patients undergoing cardiac surgery.

Product ID:

99781

Handle IRIS:

11562/971531

Last Modified:

November 28, 2022

Bibliographic citation:

Kinnunen, Eeva maija; Mosorin, Matti aleksi; Perrotti, Andrea; Ruggieri, Vito G; Svenarud, Peter; Dalén, Magnus; Onorati, Francesco; Faggian, Giuseppe; Santarpino, Giuseppe; Maselli, Daniele; Dominici, Carmelo; Nardella, Saverio; Musumeci, Francesco; Gherli, Riccardo; Mariscalco, Giovanni; Masala, Nicola; Rubino, Antonino S; Mignosa, Carmelo; De Feo, Marisa; Della Corte, Alessandro; Bancone, Ciro; Chocron, Sidney; Gatti, Giuseppe; Juvonen, Tatu; Biancari, Fausto, Validation of a New Classification Method of Postoperative Complications in Patients Undergoing Coronary Artery Surgery «Journal of Cardiothoracic and Vascular Anesthesia» , vol. 30 , n. 2 , 2016 , pp. 330-337

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